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1

Polysorbate degradation in biotherapeutic formulations: Identification and discussion of current root causes

Dwivedi, Mridula, Blech, Michaela, Presser, Ingo, Garidel, Patrick

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.49 MB

english, 2018

2

Lipid-based nanoparticle formulations for small molecules and RNA drugs

Ickenstein, Ludger M., Garidel, Patrick

Journal:

Expert Opinion on Drug Delivery

Year:

2019

Language:

english

File:

PDF, 1.76 MB

english, 2019

3

Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

John den Engelsman, Patrick Garidel, Ronald Smulders, Hans Koll, Bryan Smith, Stefan Bassarab, Andreas Seidl, Otmar Hainzl, Wim Jiskoot

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 222 KB

english, 2011

4

Sensitivity of coccolithophores to carbonate chemistry and ocean acidification

Beaufort, L., Probert, I., de Garidel-Thoron, T., Bendif, E. M., Ruiz-Pino, D., Metzl, N., Goyet, C., Buchet, N., Coupel, P., Grelaud, M., Rost, B., Rickaby, R. E. M., de Vargas, C.

Journal:

Year:

2011

Language:

english

File:

PDF, 622 KB

english, 2011

5

Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins I: Stability after freeze-drying

K. Schersch, O. Betz, P. Garidel, S. Muehlau, S. Bassarab, G. Winter

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

6

Method for identifying putrefied corpses by facial casting

Gérald Quatrehomme, Yves Garidel, Gilles Grevin, Zhigang Liao, Paul Bailet, Amédée Oillier

Journal:

Forensic Science International

Year:

1995

Language:

english

File:

PDF, 2.78 MB

english, 1995

7

Physicochemical properties of bacterial glycopolymers in relation to bioactivity

Klaus Brandenburg, Jörg Andrä, Mareike Müller, Michel H.J Koch, Patrick Garidel

Journal:

Carbohydrate Research

Year:

2003

Language:

english

File:

PDF, 631 KB

english, 2003

8

Synthesis, control of substitution pattern and phase transitions of 2,3-di-O-methylcellulose

Holger Kern, SooWhan Choi, Gerhard Wenz, Jürgen Heinrich, Lutz Ehrhardt, Petra Mischnick, Patrick Garidel, Alfred Blume

Journal:

Carbohydrate Research

Year:

2000

Language:

english

File:

PDF, 208 KB

english, 2000

9

Effects of the nonsteroidal anti-inflammatory drug naproxen on human erythrocytes and on cell membrane molecular models

Marcela Manrique-Moreno, Mario Suwalsky, Fernando Villena, Patrick Garidel

Journal:

Biophysical Chemistry

Year:

2010

Language:

english

File:

PDF, 969 KB

english, 2010

10

Solubilization of negatively charged DPPC/DPPG liposomes by bile salts

Annegret Hildebrand, Katja Beyer, Reinhard Neubert, Patrick Garidel, Alfred Blume

Journal:

Journal of Colloid and Interface Science

Year:

2004

Language:

english

File:

PDF, 934 KB

english, 2004

11

Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation

Lauren Mashburn-Warren, Jörg Howe, Patrick Garidel, Walter Richter, Frank Steiniger, Manfred Roessle, Klaus Brandenburg, Marvin Whiteley

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 574 KB

english, 2008

12

SPIE Proceedings [SPIE Advanced Lithography - San Jose, CA (Sunday 25 February 2007)] Emerging Lithographic Technologies XI - Structure and stability characterization of anti-adhesion self-assembled monolayers formed by vapour deposition for NIL use

Garidel, Sophie, Zelsmann, Marc, Voisin, Pauline, Rochat, Nevine, Michallon, Philippe, Lercel, Michael J.

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

13

The cryptic and the apparent reversed: lack of genetic differentiation within the morphologically diverse plexus of the planktonic foraminifer Globigerinoides sacculifer

André, Aurore, Weiner, Agnes, Quillévéré, Frédéric, Aurahs, Ralf, Morard, Raphaël, Douady, Christophe J., de Garidel-Thoron, Thibault, Escarguel, Gilles, de Vargas, Colomban, Kucera, Michal

Journal:

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

14

Boosting antibody developability through rational sequence optimization

Seeliger, Daniel, Schulz, Patrick, Litzenburger, Tobias, Spitz, Julia, Hoerer, Stefan, Blech, Michaela, Enenkel, Barbara, Studts, Joey M, Garidel, Patrick, Karow, Anne R

Journal:

Year:

2015

Language:

english

File:

PDF, 718 KB

english, 2015

15

Improved release strategy for UV nanoimprint lithography

S. Garidel, M. Zelsmann, N. Chaix, P. Voisin, J. Boussey, A. Beaurain, B. Pelissier

Year:

2007

Language:

english

File:

PDF, 690 KB

english, 2007

16

Resolving power of dynamic light scattering for protein and polystyrene nanoparticles

Karow, Anne R., Götzl, Jana, Garidel, Patrick

Journal:

Pharmaceutical Development and Technology

Year:

2015

Language:

english

File:

PDF, 572 KB

english, 2015

17

Hydrogel formulations for biologicals: current spotlight from a commercial perspective

Ickenstein, Ludger M, Garidel, Patrick

Journal:

Therapeutic Delivery

Year:

2018

Language:

english

File:

PDF, 509 KB

english, 2018

18

Acidic and alkaline hydrolysis of polysorbates under aqueous conditions: Towards understanding polysorbate degradation in biopharmaceutical formulations.

Dwivedi, Mridula, Buske, Julia, Haemmerling, Frank, Blech, Michaela, Patrick, Garidel

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 909 KB

2020

19

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80

GlÃ¼cklich, Nils, Dwivedi, Mridula, Carle, Stefan, Buske, Julia, MÃ¤der, Karsten, Garidel, Patrick

Journal:

International Journal of Pharmaceutics

Year:

2020

File:

PDF, 1.71 MB

2020

20

Mid infrared microspectroscopic mapping and imaging: A bio-analytical tool for spatially and chemically resolved tissue characterization and evaluationof drug permeation within tissues

Patrick Garidel, Matthias Boese

Journal:

Microscopy Research and Technique

Year:

2007

Language:

english

File:

PDF, 1.92 MB

english, 2007

21

Apodized Bragg filters on InP-materials ridge waveguides using sampled gratings

S. Garidel, D. Lauvernier, J. P. Vilcot, M. François, D. Decoster

Journal:

Microwave and Optical Technology Letters

Year:

2006

Language:

english

File:

PDF, 295 KB

english, 2006

22

Versatile bondpad report process for non-planar compound semiconductor devices

Sophie Garidel, Jean-Pierre Vilcot, Mohammed Zaknoune, Pascal Tilmant

Journal:

Microelectronic Engineering

Year:

2004

Language:

english

File:

PDF, 317 KB

english, 2004

23

A thermodynamic analysis of the binding interaction between polysorbate 20 and 80 with human serum albumins and immunoglobulins: A contribution to understand colloidal protein stabilisation

Patrick Garidel, Claudia Hoffmann, Alfred Blume

Journal:

Biophysical Chemistry

Year:

2009

Language:

english

File:

PDF, 1013 KB

english, 2009

24

Molecular basis for endotoxin neutralization by amphipathic peptides derived from the α-helical cationic core-region of NK-lysin

Klaus Brandenburg, Patrick Garidel, Satoshi Fukuoka, Jörg Howe, Michel H.J. Koch, Thomas Gutsmann, Jörg Andrä

Journal:

Biophysical Chemistry

Year:

2010

Language:

english

File:

PDF, 829 KB

english, 2010

25

The microstructure of the stratum corneum lipid barrier: Mid-infrared spectroscopic studies of hydrated ceramide:palmitic acid:cholesterol model systems

Patrick Garidel, Bettina Fölting, Ingrid Schaller, Andreas Kerth

Journal:

Biophysical Chemistry

Year:

2010

Language:

english

File:

PDF, 1.94 MB

english, 2010

26

Membrane Interacting Peptides - Towards the Understanding of Biological Membranes

Patrick Garidel, Andreas Kerth, Roland Winter

Journal:

Biophysical Chemistry

Year:

2010

Language:

english

File:

PDF, 93 KB

english, 2010

27

1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) monolayers: influence of temperature, pH, ionic strength and binding of alkaline earth cations

Patrick Garidel, Alfred Blume

Journal:

Chemistry and Physics of Lipids

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

28

Structural polymorphism of hydrated ether-linked dimyristyl maltoside and melibioside

Patrick Garidel, Jörg Howe, Götz Milkereit, Manfred Rössle, Sebastian Linser, Sven Gerber, Regine Willumeit, Thomas Gutsmann, Volkmar Vill, Klaus Brandenburg

Journal:

Chemistry and Physics of Lipids

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

29

Phase diagrams of monoacylated amide-linked disaccharide glycolipids

S. Gerber, M. Wulf, G. Milkereit, V. Vill, J. Howe, M. Roessle, P. Garidel, T. Gutsmann, K. Brandenburg

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 1.57 MB

english, 2009

30

Temperature dependence of the interaction of cholate and deoxycholate with fluid model membranes and their solubilization into mixed micelles

Annegret Hildebrand, Katja Beyer, Reinhard Neubert, Patrick Garidel, Alfred Blume

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2003

Language:

english

File:

PDF, 1.25 MB

english, 2003

31

Realization of sub-micron patterns on GaAs using a HSQ etching mask

Denis Lauvernier, Sophie Garidel, Christiane Legrand, Jean-Pierre Vilcot

Journal:

Microelectronic Engineering

Year:

2005

Language:

english

File:

PDF, 480 KB

english, 2005

32

What can calorimetry tell us about changes of three-dimensional aggregate structures of phospholipids and glycolipids?

K. Brandenburg, P. Garidel, J. Howe, J. Andrä, L. Hawkins, M.H.J. Koch, U. Seydel

Journal:

Thermochimica Acta

Year:

2006

Language:

english

File:

PDF, 839 KB

english, 2006

33

Packing characteristics of a model system mimicking cytoplasmic bacterial membranes

Karl Lohner, Angelika Latal, Gábor Degovics, Patrick Garidel

Journal:

Chemistry and Physics of Lipids

Year:

2001

Language:

english

File:

PDF, 285 KB

english, 2001

34

Biomass burning and oceanic primary production estimates in the Sulu Sea area over the last 380 kyr and the East Asian monsoon dynamics

L Beaufort, T de Garidel-Thoron, B Linsley, D Oppo, N Buchet

Journal:

Year:

2003

Language:

english

File:

PDF, 858 KB

english, 2003

35

Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins

Klaus Brandenburg, Gudrun Jürgens, Jörg Andrä, Buko Lindner, Michel H. J. Koch, Alfred Blume, Patrick Garidel

Journal:

Year:

2002

Language:

english

File:

PDF, 513 KB

english, 2002

36

Physicochemical characterization of the endotoxins fromCoxiella burnetiistrain Priscilla in relation to their bioactivities

Rudolf Toman, Patrick Garidel, Jörg Andrä, Katarina Slaba, Ahmed Hussein, Michel HJ Koch, Klaus Brandenburg

Journal:

BMC Biochemistry

Year:

2004

Language:

english

File:

PDF, 326 KB

english, 2004

37

Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes

Klaus Brandenburg, Patrick Garidel, Andra B. Schromm, Jörg Andrä, Arjen Kramer, Maarten Egmond, Andre Wiese

Journal:

European Biophysics Journal

Year:

2005

Language:

english

File:

PDF, 473 KB

english, 2005

38

Hydrophobic interactions are the driving force for the binding of peptide mimotopes andStaphylococcalprotein A to recombinant human IgG1

Ahmad Arouri, Patrick Garidel, Werner Kliche, Alfred Blume

Journal:

European Biophysics Journal

Year:

2007

Language:

english

File:

PDF, 344 KB

english, 2007

39

Insights into protein–polysorbate interactions analysed by means of isothermal titration and differential scanning calorimetry

Claudia Hoffmann, Alfred Blume, Inge Miller, Patrick Garidel

Journal:

European Biophysics Journal

Year:

2009

Language:

english

File:

PDF, 800 KB

english, 2009

40

Non-ideal mixing and fluid–fluid immiscibility in phosphatidic acid–phosphatidylethanolamine mixed bilayers

Patrick Garidel, Christof Johann, Alfred Blume

Journal:

European Biophysics Journal

Year:

2011

Language:

english

File:

PDF, 934 KB

english, 2011

41

Miscibility of phosphatidylethanolamine-phosphatidylglycerol mixtures as a function of pH and acyl chain length

Patrick Garidel, Alfred Blume

Journal:

European Biophysics Journal

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

42

The mixing behavior of pseudobinary phosphatidylcholine-phosphatidylglycerol mixtures as a function of pH and chain length

Patrick Garidel, Christof Johann, Lutz Mennicke, A. Blume

Journal:

European Biophysics Journal

Year:

1997

Language:

english

File:

PDF, 1.49 MB

english, 1997

43

Peptide-based treatment of sepsis

Klaus Brandenburg, Jörg Andrä, Patrick Garidel, Thomas Gutsmann

Journal:

Applied Microbiology and Biotechnology

Year:

2011

Language:

english

File:

PDF, 395 KB

english, 2011

44

Thermodynamic properties of association colloids

P. Garidel, A. Hildebrand

Journal:

Journal of Thermal Analysis and Calorimetry

Year:

2005

Language:

english

File:

PDF, 414 KB

english, 2005

45

The calculation of heat capacity curves and phase diagrams based on regular solution theory

P. Garidel, C. Johann, A. Blume

Journal:

Journal of Thermal Analysis and Calorimetry

Year:

2005

Language:

english

File:

PDF, 575 KB

english, 2005

46

Structural polymorphism of hydrated monoacylated maltose glycolipids

Jörg Howe, Patrick Garidel, Matthias Wulf, Sven Gerber, Götz Milkereit, Volkmar Vill, Manfred Roessle, Klaus Brandenburg

Journal:

Chemistry and Physics of Lipids

Year:

2008

Language:

english

File:

PDF, 664 KB

english, 2008

47

Air-bridge interconnection and bondpad process for non-planar compound semiconductor devices

Gwenn Ulliac, Sophie Garidel, Jean-Pierre Vilcot, Pascal Tilmant

Journal:

Microelectronic Engineering

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005

48

Biophysical characterization of the interaction of Limulus polyphemus endotoxin neutralizing protein with lipopolysaccharide

Jörg Andrä, Patrick Garidel, Andreja Majerle, Roman Jerala, Richard Ridge, Erik Paus, Tom Novitsky, Michel H. J. Koch, Klaus Brandenburg

Journal:

Year:

2004

Language:

english

File:

PDF, 507 KB

english, 2004

49

Stable sea surface temperatures in the western Pacific warm pool over the past 1.75 million years

de Garidel-Thoron, Thibault, Rosenthal, Yair, Bassinot, Franck, Beaufort, Luc

Journal:

Year:

2005

Language:

english

File:

PDF, 378 KB

english, 2005

50

Transfection Efficiency and Cytotoxicity of Nonviral Gene Transfer Reagents in Human Smooth Muscle and Endothelial Cells

Karin Kiefer, Jule Clement, Patrick Garidel, Regine Peschka-Süss

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 357 KB

english, 2004